Cytotoxicity of Cultured Canine Primary Hepatocytes Exposed to Itraconazole Is Decreased by Pre-treatment With Glutathione

Objective: To identify the effect of glutathione (GSH) on cell survival in a novel in vitro model of itraconazole (ITZ)-associated hepatotoxicity using canine primary hepatocytes. Sample: Commercially sourced, cryopreserved male dog (Beagle) primary hepatocytes from a single donor. Procedures: Using...

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Detalles Bibliográficos
Autores principales: Kirk, Natalie M., Vieson, Miranda D., Selting, Kim A., Reinhart, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930617/
https://www.ncbi.nlm.nih.gov/pubmed/33681327
http://dx.doi.org/10.3389/fvets.2021.621732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930617/
https://www.ncbi.nlm.nih.gov/pubmed/33681327
http://dx.doi.org/10.3389/fvets.2021.621732

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