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Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells

The proprotein convertase enzyme FURIN promotes the proteolytic maturation of pro-proteins and thereby it serves as an important factor for maintaining cellular homeostasis. In T cells, FURIN is critical for maintaining the T regulatory cell dependent peripheral immune tolerance and intact T helper...

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Detalles Bibliográficos
Autores principales: Ortutay, Zsuzsanna, Grönholm, Anna, Laitinen, Melina, Keresztes-Andrei, Melinda, Hermelo, Ismail, Pesu, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930619/
https://www.ncbi.nlm.nih.gov/pubmed/33679774
http://dx.doi.org/10.3389/fimmu.2021.630389