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Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells
The proprotein convertase enzyme FURIN promotes the proteolytic maturation of pro-proteins and thereby it serves as an important factor for maintaining cellular homeostasis. In T cells, FURIN is critical for maintaining the T regulatory cell dependent peripheral immune tolerance and intact T helper...
Autores principales: | Ortutay, Zsuzsanna, Grönholm, Anna, Laitinen, Melina, Keresztes-Andrei, Melinda, Hermelo, Ismail, Pesu, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930619/ https://www.ncbi.nlm.nih.gov/pubmed/33679774 http://dx.doi.org/10.3389/fimmu.2021.630389 |
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