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Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis

Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of mitophagy can promote bone marrow mesenchymal stem cells (BMSCs) senescence, and increasing studies have shown that int...

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Detalles Bibliográficos
Autores principales: Guo, Yuanyuan, Jia, Xiong, Cui, Yongzhi, Song, Yu, Wang, Siyuan, Geng, Yongtao, Li, Rui, Gao, Weihang, Fu, Dehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930642/
https://www.ncbi.nlm.nih.gov/pubmed/33662874
http://dx.doi.org/10.1016/j.redox.2021.101915