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Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis
Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of mitophagy can promote bone marrow mesenchymal stem cells (BMSCs) senescence, and increasing studies have shown that int...
Autores principales: | Guo, Yuanyuan, Jia, Xiong, Cui, Yongzhi, Song, Yu, Wang, Siyuan, Geng, Yongtao, Li, Rui, Gao, Weihang, Fu, Dehao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930642/ https://www.ncbi.nlm.nih.gov/pubmed/33662874 http://dx.doi.org/10.1016/j.redox.2021.101915 |
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