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IL-10 and TGF-β Induced Arginase Expression Contributes to Deficient Nitric Oxide Response in Human Visceral Leishmaniasis

Nitric oxide (NO) is an anti-microbial effector of the innate immune system which plays major role in non-specific killing of various pathogens including protozoan parasites. However, due to subversion of the host’s immune processes by pathogens, suboptimal production of NO is frequently found in ma...

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Detalles Bibliográficos
Autores principales: Kupani, Manu, Sharma, Smriti, Pandey, Rajeev Kumar, Kumar, Rajiv, Sundar, Shyam, Mehrotra, Sanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930829/
https://www.ncbi.nlm.nih.gov/pubmed/33680983
http://dx.doi.org/10.3389/fcimb.2020.614165