Life-Threatening Influenza, Hemophagocytic Lymphohistiocytosis and Probable Vaccine-Strain Varicella in a Novel Case of Homozygous STAT2 Deficiency

STAT2 is a transcription factor that plays an essential role in antiviral immunity by mediating the activity of type I and III interferons (IFN-I and IFN-III). It also has a recently established function in the negative regulation of IFN-I signaling. Homozygous STAT2 deficiency is an ultra-rare inbo...

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Detalles Bibliográficos
Autores principales: Freij, Bishara J., Hanrath, Aidan T., Chen, Rui, Hambleton, Sophie, Duncan, Christopher J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930908/
https://www.ncbi.nlm.nih.gov/pubmed/33679716
http://dx.doi.org/10.3389/fimmu.2020.624415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930908/
https://www.ncbi.nlm.nih.gov/pubmed/33679716
http://dx.doi.org/10.3389/fimmu.2020.624415

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