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Hydrogen sulfide ameliorates doxorubicin-induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway

The present study aimed to determine the role and regulatory mechanism of hydrogen sulfide (H(2)S) in the amelioration of doxorubicin-induced myocardial fibrosis in rats. It is hypothesized that the PI3K/AKT/mTOR signaling pathway is regulated to inhibit endoplasmic reticulum stress (ERS) and autoph...

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Detalles Bibliográficos
Autores principales: Nie, Liangui, Liu, Maojun, Chen, Jian, Wu, Qian, Li, Yaling, Yi, Jiali, Zheng, Xia, Zhang, Jingjing, Chu, Chun, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930940/
https://www.ncbi.nlm.nih.gov/pubmed/33649809
http://dx.doi.org/10.3892/mmr.2021.11938