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Hydrogen sulfide ameliorates doxorubicin-induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway
The present study aimed to determine the role and regulatory mechanism of hydrogen sulfide (H(2)S) in the amelioration of doxorubicin-induced myocardial fibrosis in rats. It is hypothesized that the PI3K/AKT/mTOR signaling pathway is regulated to inhibit endoplasmic reticulum stress (ERS) and autoph...
Autores principales: | Nie, Liangui, Liu, Maojun, Chen, Jian, Wu, Qian, Li, Yaling, Yi, Jiali, Zheng, Xia, Zhang, Jingjing, Chu, Chun, Yang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930940/ https://www.ncbi.nlm.nih.gov/pubmed/33649809 http://dx.doi.org/10.3892/mmr.2021.11938 |
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