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A Modified Limiting Dilution Method for Monoclonal Stable Cell Line Selection Using a Real-Time Fluorescence Imaging System: A Practical Workflow and Advanced Applications

Stable cell lines are widely used in laboratory research and pharmaceutical industry. They are mainly applied in recombinant protein and antibody productions, gene function studies, drug screens, toxicity assessments, and for cancer therapy investigation. There are two types of cell lines, polyclona...

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Detalles Bibliográficos
Autores principales: Ye, Mingyu, Wilhelm, Martina, Gentschev, Ivaylo, Szalay, Aladár
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931037/
https://www.ncbi.nlm.nih.gov/pubmed/33672596
http://dx.doi.org/10.3390/mps4010016