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Mechanism of Interactions of dsDNA Binding with Apigenin and Its Sulfamate Derivatives Using Multispectroscopic, Voltammetric, and Molecular Docking Studies

[Image: see text] DNA binding investigations are critical for designing better pharmaceutical compounds since the binding of a compound to dsDNA in the minor groove is critical in drug discovery. Although only one in vitro study on the DNA binding mode of apigenin (APG) has been conducted, there hav...

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Detalles Bibliográficos
Autores principales: Waihenya, Simon, Şenel, Pelin, Osonga, Francis J., Erdoğan, Taner, Altay, Filiz, Gölcü, Ayşegül, Sadik, Omowunmi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931193/
https://www.ncbi.nlm.nih.gov/pubmed/33681554
http://dx.doi.org/10.1021/acsomega.0c02612