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Preclinical efficacy and toxicity studies of a highly specific chimeric anti‐CD47 antibody

Cluster of differentiation 47 (CD47) is a widely expressed self‐protection transmembrane protein that functions as a critical negative regulator to induce macrophage‐mediated phagocytosis. Overexpression of CD47 enables cancer cells to escape immune surveillance and destruction by phagocytes both in...

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Detalles Bibliográficos
Autores principales: Xu, Zhiqiang, Gao, Jing, Yao, Jingyun, Yang, Teddy, Wang, Dongxu, Dai, Chaohui, Ding, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931223/
https://www.ncbi.nlm.nih.gov/pubmed/33449453
http://dx.doi.org/10.1002/2211-5463.13084