Novel Chiral Thiourea Derived from Hydroquinine and l-Phenylglycinol: An Effective Catalyst for Enantio- and Diastereoselective Aza-Henry Reaction

[Image: see text] A series of chiral thiourea bearing multiple H-bond donors derived from hydroquinine has been reported. The aza-Henry reaction of isatin-derived ketimines and long-chain nitroalkanes catalyzed by these chiral thioureas can achieve high enantioselectivity (78–99% ee) and excellent d...

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Detalles Bibliográficos
Autores principales: Wang, Jingdong, Liu, Yuxin, Wei, Zhonglin, Cao, Jungang, Liang, Dapeng, Lin, Yingjie, Duan, Hai-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931441/
https://www.ncbi.nlm.nih.gov/pubmed/33681620
http://dx.doi.org/10.1021/acsomega.0c06233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931441/
https://www.ncbi.nlm.nih.gov/pubmed/33681620
http://dx.doi.org/10.1021/acsomega.0c06233

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