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Novel Chiral Thiourea Derived from Hydroquinine and l-Phenylglycinol: An Effective Catalyst for Enantio- and Diastereoselective Aza-Henry Reaction

[Image: see text] A series of chiral thiourea bearing multiple H-bond donors derived from hydroquinine has been reported. The aza-Henry reaction of isatin-derived ketimines and long-chain nitroalkanes catalyzed by these chiral thioureas can achieve high enantioselectivity (78–99% ee) and excellent d...

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Detalles Bibliográficos
Autores principales:	Wang, Jingdong, Liu, Yuxin, Wei, Zhonglin, Cao, Jungang, Liang, Dapeng, Lin, Yingjie, Duan, Hai-feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931441/ https://www.ncbi.nlm.nih.gov/pubmed/33681620 http://dx.doi.org/10.1021/acsomega.0c06233

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