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Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer

[Image: see text] Despite the astonishing diversity of naturally occurring biocatalytic processes, enzymes do not catalyze many of the transformations favored by synthetic chemists. Either nature does not care about the specific products, or if she does, she has adopted a different synthetic strateg...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931446/
https://www.ncbi.nlm.nih.gov/pubmed/33491448
http://dx.doi.org/10.1021/acs.accounts.0c00591