Pentoxifylline Sensitizes Cisplatin-Resistant Human Cervical Cancer Cells to Cisplatin Treatment: Involvement of Mitochondrial and NF-Kappa B Pathways

BACKGROUND: Cervical cancer continues to be a major public health problem worldwide, and Cisplatin is used as first-line chemotherapy for this cancer; however, malignant cells exposed to CISplatin (CIS) become insensitive to the effects of this drug. PenToXifylline (PTX) is a xanthine that sensitize...

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Detalles Bibliográficos
Autores principales: Bravo-Cuellar, Alejandro, Ortiz-Lazareno, Pablo Cesar, Sierra-Díaz, Erick, Solorzano-Ibarra, Fabiola, Méndez-Clemente, Anibal Samael, Aguilar-Lemarroy, Adriana, Jave-Suárez, Luis Felipe, Ruiz Velazco-Niño, Édgar, Hernández-Flores, Georgina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931705/
https://www.ncbi.nlm.nih.gov/pubmed/33680921
http://dx.doi.org/10.3389/fonc.2020.592706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931705/
https://www.ncbi.nlm.nih.gov/pubmed/33680921
http://dx.doi.org/10.3389/fonc.2020.592706

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