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Intrahepatic cholangiocarcinoma in a non-cirrhotic liver in a patient with homozygous ZZ alpha-1 antitrypsin deficiency

Alpha-1 antitrypsin (AAT) deficiency, which is an under-recognised metabolic genetic disorder, is known to cause severe lung disease and liver cirrhosis in about 10%–15% of cases. Patients with AAT deficiency are at a higher risk for developing hepatocellular carcinoma, both in cirrhotic and in non-...

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Detalles Bibliográficos
Autores principales: Vuurberg, Nienke E, Van den Boom, Anne Loes, Van den Heuvel, Marius C, Klaase, Joost M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931763/
https://www.ncbi.nlm.nih.gov/pubmed/33658218
http://dx.doi.org/10.1136/bcr-2020-240077