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hsa-miR-4443 inhibits myocardial fibroblast proliferation by targeting THBS1 to regulate TGF-β1/α-SMA/collagen signaling in atrial fibrillation

Fibrosis caused by the increase in extracellular matrix in cardiac fibroblasts plays an important role in the occurrence and development of atrial fibrillation (AF). The aim of this study was to investigate the role of hsa-miR-4443 in AF, human cardiac fibroblast (HCFB) proliferation, and extracellu...

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Detalles Bibliográficos
Autores principales: Xiao, Jingwen, Zhang, Yan, Tang, Yuan, Dai, Hengfen, OuYang, Yu, Li, Chuanchuan, Yu, Meiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931814/
https://www.ncbi.nlm.nih.gov/pubmed/33681892
http://dx.doi.org/10.1590/1414-431X202010692