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Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition

Ensuring the safety of new drugs is critically important to regulators, pharmaceutical researchers and patients alike. Even so, unexpected toxicities still account for 20–30% of clinical trial failures, in part due to the persistence of animal testing as the primary approach for de-risking new drugs...

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Detalles Bibliográficos
Autor principal: Berg, Ellen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931891/
https://www.ncbi.nlm.nih.gov/pubmed/33693370
http://dx.doi.org/10.3389/fdata.2019.00047