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No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis

BACKGROUND: Reduced heart rate (HR) increase (HRI), recovery (HRR), and higher resting HR are associated with cardiovascular (CV) disease, but causal inferences have not been deduced. We investigated causal effects of HRI, HRR, and resting HR on CV risk, all-cause mortality (ACM), atrial fibrillatio...

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Detalles Bibliográficos
Autores principales: Mensah-Kane, Josephine, Schmidt, Amand F., Hingorani, Aroon D., Finan, Chris, Chen, Yutang, van Duijvenboden, Stefan, Orini, Michele, Lambiase, Pier D., Tinker, Andrew, Marouli, Eirini, Munroe, Patricia B., Ramírez, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931909/
https://www.ncbi.nlm.nih.gov/pubmed/33679875
http://dx.doi.org/10.3389/fgene.2021.569323