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No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis
BACKGROUND: Reduced heart rate (HR) increase (HRI), recovery (HRR), and higher resting HR are associated with cardiovascular (CV) disease, but causal inferences have not been deduced. We investigated causal effects of HRI, HRR, and resting HR on CV risk, all-cause mortality (ACM), atrial fibrillatio...
Autores principales: | Mensah-Kane, Josephine, Schmidt, Amand F., Hingorani, Aroon D., Finan, Chris, Chen, Yutang, van Duijvenboden, Stefan, Orini, Michele, Lambiase, Pier D., Tinker, Andrew, Marouli, Eirini, Munroe, Patricia B., Ramírez, Julia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931909/ https://www.ncbi.nlm.nih.gov/pubmed/33679875 http://dx.doi.org/10.3389/fgene.2021.569323 |
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