TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals

Genotoxicity testing is an essential component of the safety assessment paradigm required by regulatory agencies world-wide for analysis of drug candidates, and environmental and industrial chemicals. Current genotoxicity testing batteries feature a high incidence of irrelevant positive findings—par...

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Detalles Bibliográficos
Autores principales: Li, Heng-Hong, Yauk, Carole L., Chen, Renxiang, Hyduke, Daniel R., Williams, Andrew, Frötschl, Roland, Ellinger-Ziegelbauer, Heidrun, Pettit, Syril, Aubrecht, Jiri, Fornace, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Big Data
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931968/
https://www.ncbi.nlm.nih.gov/pubmed/33693359
http://dx.doi.org/10.3389/fdata.2019.00036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931968/
https://www.ncbi.nlm.nih.gov/pubmed/33693359
http://dx.doi.org/10.3389/fdata.2019.00036

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