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Isoalantolactone inhibits pancreatic cancer proliferation by regulation of PI3K and Wnt signal pathway

BACKGROUND/AIMS: Isoalantolactone (IATL) is one of multiple isomeric sesquiterpene lactones and is isolated from inula helenium. IATL has multiple functions such as antibacterial, antihelminthic and antiproliferative activities. IATL also inhibits pancreatic cancer proliferation and induces apoptosi...

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Detalles Bibliográficos
Autores principales: Zhang, Chaoxiong, Huang, Lei, Xiong, Jingyuan, Xie, Linshen, Ying, Shi, Jia, You, Yao, Yuqin, Song, Xuejiao, Zeng, Zhenguo, Yuan, Jialing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932101/
https://www.ncbi.nlm.nih.gov/pubmed/33661942
http://dx.doi.org/10.1371/journal.pone.0247752