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The pronounced lung lesions developing in LAT(Y136F) knock-in mice mimic human IgG4-related lung disease
RATIONALE: Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a novel clinical disease entity characterized by an elevated serum IgG4 concentration and tumefaction or tissue infiltration by IgG4-positive plasma cells. Pathological changes are most frequently seen in the pancreas, lacrimal glands, a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932159/ https://www.ncbi.nlm.nih.gov/pubmed/33661938 http://dx.doi.org/10.1371/journal.pone.0247173 |