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Effector memory CD8 T cell response elicits Hepatitis E Virus genotype 3 pathogenesis in the elderly

Genotype 3 Hepatitis E virus (HEV-3) is an emerging threat for aging population. More than one third of older infected patients develops clinical symptoms with severe liver damage, while others remain asymptomatic. The origin of this discrepancy is still elusive although HEV-3 pathogenesis appears t...

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Detalles Bibliográficos
Autores principales: El Costa, Hicham, Gouilly, Jordi, Abravanel, Florence, Bahraoui, Elmostafa, Peron, Jean-Marie, Kamar, Nassim, Jabrane-Ferrat, Nabila, Izopet, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932504/
https://www.ncbi.nlm.nih.gov/pubmed/33617602
http://dx.doi.org/10.1371/journal.ppat.1009367