A mathematical model of the role of aggregation in sonic hedgehog signalling

Effective regulation of the sonic hedgehog (Shh) signalling pathway is essential for normal development in a wide variety of species. Correct Shh signalling requires the formation of Shh aggregates on the surface of producing cells. Shh aggregates subsequently diffuse away and are recognised in rece...

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Detalles Bibliográficos
Autores principales: Derrick, Daniel J. A., Wolton, Kathryn, Currie, Richard A., Tindall, Marcus John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932509/
https://www.ncbi.nlm.nih.gov/pubmed/33617524
http://dx.doi.org/10.1371/journal.pcbi.1008562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932509/
https://www.ncbi.nlm.nih.gov/pubmed/33617524
http://dx.doi.org/10.1371/journal.pcbi.1008562

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