2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profiling

Leishmaniasis is a major infectious disease with hundreds of thousands of new cases and over 20,000 deaths each year. The current drugs to treat this life-threatening infection have several drawbacks such as toxicity and long treatment regimens. A library of 1.8 million compounds, from which the hit...

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Detalles Bibliográficos
Autores principales: Ferreira, Rafael Augusto Alves, Junior, Celso de Oliveira Rezende, Martinez, Pablo David Grigol, Koovits, Paul John, Soares, Bruna Miranda, Ferreira, Leonardo L. G., Michelan-Duarte, Simone, Chelucci, Rafael Consolin, Andricopulo, Adriano D., Galuppo, Mariana K., Uliana, Silvia R. B., Matheeussen, An, Caljon, Guy, Maes, Louis, Campbell, Simon, Kratz, Jadel M., Mowbray, Charles E., Dias, Luiz Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932521/
https://www.ncbi.nlm.nih.gov/pubmed/33617566
http://dx.doi.org/10.1371/journal.pntd.0009196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932521/
https://www.ncbi.nlm.nih.gov/pubmed/33617566
http://dx.doi.org/10.1371/journal.pntd.0009196

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