DeepSRE: Identification of sterol responsive elements and nuclear transcription factors Y proximity in human DNA by Convolutional Neural Network analysis

SREBP1 and 2, are cholesterol sensors able to modulate cholesterol-related gene expression responses. SREBPs binding sites are characterized by the presence of multiple target sequences as SRE, NFY and SP1, that can be arranged differently in different genes, so that it is not easy to identify the b...

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Detalles Bibliográficos
Autores principales: Noto, Davide, Giammanco, Antonina, Spina, Rossella, Fayer, Francesca, Cefalù, Angelo B., Averna, Maurizio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932541/
https://www.ncbi.nlm.nih.gov/pubmed/33661949
http://dx.doi.org/10.1371/journal.pone.0247402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932541/
https://www.ncbi.nlm.nih.gov/pubmed/33661949
http://dx.doi.org/10.1371/journal.pone.0247402

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