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Identifying molecular features that are associated with biological function of intrinsically disordered protein regions

In previous work, we showed that intrinsically disordered regions (IDRs) of proteins contain sequence-distributed molecular features that are conserved over evolution, despite little sequence similarity that can be detected in alignments (Zarin et al., 2019). Here, we aim to use these molecular feat...

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Detalles Bibliográficos
Autores principales: Zarin, Taraneh, Strome, Bob, Peng, Gang, Pritišanac, Iva, Forman-Kay, Julie D, Moses, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932695/
https://www.ncbi.nlm.nih.gov/pubmed/33616531
http://dx.doi.org/10.7554/eLife.60220