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Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Hepatic Stellate Cell Activation and Liver Fibrosis by Upregulating MicroRNA-455-3p through Suppression of p21-Activated Kinase-2

Mesenchymal stem cells (MSCs) were shown to have potential therapeutic effects for treatment of liver fibrosis, and dysregulated expression of microRNAs (miRNAs) played a pivotal role in the pathogenesis of liver fibrosis by regulating their downstream target genes. However, the mechanism by which M...

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Detalles Bibliográficos
Autores principales: Zhou, Qing, Gu, Tengfei, Zhang, Yong, Li, Hongda, Zhuansun, Xuemei, Xu, Sanrong, Kuang, Yuting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932777/
https://www.ncbi.nlm.nih.gov/pubmed/33708992
http://dx.doi.org/10.1155/2021/6685605