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A Direct and Sensitive Method for Determination of 5-Fluorouracil in Colorectal Cancer Cells: Evaluating the Effect of Stromal Cell on Drug Resistance of Cancer Cells

Fibroblasts in the stroma play a critical role in tumor evolution. In this study, we assessed the influence of colonic fibroblasts on colon cancer cells treated with 5-fluorouracil (5-FU), and mouse colon cancer cell lines MC38 and colonic fibroblasts NIH3T3 were used in this study. A sensitive and...

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Detalles Bibliográficos
Autores principales: Xu, Fengjing, Wang, Zhipeng, Song, Xinhua, Zhang, Mengwei, Cui, Lili, Liu, Yanping, Yan, Hongxia, Gao, Shouhong, Liu, Yan, Chen, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932793/
https://www.ncbi.nlm.nih.gov/pubmed/33708454
http://dx.doi.org/10.1155/2021/6689488