A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis

Classification of acute lymphoblastic and myeloid leukemias (ALL and AML) remains heavily based on phenotypic resemblance to normal hematopoietic precursors. This framework can provide diagnostic challenges for immunophenotypically heterogeneous immature leukemias, and ignores recent advances in und...

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Detalles Bibliográficos
Autores principales: Bond, Jonathan, Krzywon, Aleksandra, Lhermitte, Ludovic, Roumier, Christophe, Roggy, Anne, Belhocine, Mohamed, Kheirallah, Alexander Abdulkader, Villarese, Patrick, Hypolite, Guillaume, Garnache-Ottou, Francine, Castaigne, Sylvie, Boissel, Nicolas, Asnafi, Vahid, Preudhomme, Claude, Dombret, Hervé, Laurenti, Elisa, Macintyre, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932917/
https://www.ncbi.nlm.nih.gov/pubmed/32655144
http://dx.doi.org/10.1038/s41375-020-0965-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932917/
https://www.ncbi.nlm.nih.gov/pubmed/32655144
http://dx.doi.org/10.1038/s41375-020-0965-z

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