The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions

Solid tumors are often characterized by a hypoxic microenvironment which contributes, through the hypoxia-inducible factor HIF-1, to the invasion-metastasis cascade. Endoplasmic reticulum (ER) stress also leads tumor cells to thrive and spread by inducing a transcriptional and translational program,...

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Detalles Bibliográficos
Autores principales: Varone, Ersilia, Decio, Alessandra, Chernorudskiy, Alexander, Minoli, Lucia, Brunelli, Laura, Ioli, Federica, Piotti, Arianna, Pastorelli, Roberta, Fratelli, Maddalena, Gobbi, Marco, Giavazzi, Raffaella, Zito, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932925/
https://www.ncbi.nlm.nih.gov/pubmed/33531624
http://dx.doi.org/10.1038/s41388-021-01659-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932925/
https://www.ncbi.nlm.nih.gov/pubmed/33531624
http://dx.doi.org/10.1038/s41388-021-01659-y

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