NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway

Aberrant Notch activation has been implicated in multiple malignancies and the identification of NOTCH receptors and related pathways is critical for targeted therapy. In this study, we aim to delineate the most prominent dysregulated NOTCH receptor and comprehensively reveal its deregulation in gas...

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Detalles Bibliográficos
Autores principales: Kang, Wei, Zhang, Jinglin, Huang, Tingting, Zhou, Yuhang, Wong, Chi Chun, Chan, Ronald C. K., Dong, Yujuan, Wu, Feng, Zhang, Bin, Wu, William K. K., Chan, Michael W. Y., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Lo, Kwok Wai, To, Ka Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932926/
https://www.ncbi.nlm.nih.gov/pubmed/33452458
http://dx.doi.org/10.1038/s41388-020-01579-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932926/
https://www.ncbi.nlm.nih.gov/pubmed/33452458
http://dx.doi.org/10.1038/s41388-020-01579-3

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