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NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway
Aberrant Notch activation has been implicated in multiple malignancies and the identification of NOTCH receptors and related pathways is critical for targeted therapy. In this study, we aim to delineate the most prominent dysregulated NOTCH receptor and comprehensively reveal its deregulation in gas...
Autores principales: | Kang, Wei, Zhang, Jinglin, Huang, Tingting, Zhou, Yuhang, Wong, Chi Chun, Chan, Ronald C. K., Dong, Yujuan, Wu, Feng, Zhang, Bin, Wu, William K. K., Chan, Michael W. Y., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Lo, Kwok Wai, To, Ka Fai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932926/ https://www.ncbi.nlm.nih.gov/pubmed/33452458 http://dx.doi.org/10.1038/s41388-020-01579-3 |
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