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Constitutive PGC-1α Overexpression in Skeletal Muscle Does Not Contribute to Exercise-Induced Neurogenesis

Physical exercise can improve age-dependent decline in cognition, which in rodent is partly mediated by restoration of an age-dependent decline in neurogenesis. Exercise-inducible myokines in the circulation present a link in muscle-brain crosstalk. The transcription factor PGC-1α regulates the rele...

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Detalles Bibliográficos
Autores principales: Karlsson, Lars, González-Alvarado, María Nazareth, Motalleb, Reza, Wang, Yafeng, Wang, Yong, Börjesson, Mats, Zhu, Changlian, Kuhn, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932943/
https://www.ncbi.nlm.nih.gov/pubmed/33200398
http://dx.doi.org/10.1007/s12035-020-02189-6