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Constitutive PGC-1α Overexpression in Skeletal Muscle Does Not Contribute to Exercise-Induced Neurogenesis
Physical exercise can improve age-dependent decline in cognition, which in rodent is partly mediated by restoration of an age-dependent decline in neurogenesis. Exercise-inducible myokines in the circulation present a link in muscle-brain crosstalk. The transcription factor PGC-1α regulates the rele...
Autores principales: | Karlsson, Lars, González-Alvarado, María Nazareth, Motalleb, Reza, Wang, Yafeng, Wang, Yong, Börjesson, Mats, Zhu, Changlian, Kuhn, Hans-Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932943/ https://www.ncbi.nlm.nih.gov/pubmed/33200398 http://dx.doi.org/10.1007/s12035-020-02189-6 |
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