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Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence of Neospora caninum
Neospora caninum causes abortions in cattle and nervous system dysfunction in dogs. Dense granular proteins (GRAs) play important roles in virulence; however, studies on NcGRA functions are limited. In the present study, multiple methods, including site-directed mutagenesis; CRISPR/Cas9 gene editing...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933011/ https://www.ncbi.nlm.nih.gov/pubmed/33681332 http://dx.doi.org/10.3389/fvets.2021.634612 |