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Disruption of Dense Granular Protein 2 (GRA2) Decreases the Virulence of Neospora caninum

Neospora caninum causes abortions in cattle and nervous system dysfunction in dogs. Dense granular proteins (GRAs) play important roles in virulence; however, studies on NcGRA functions are limited. In the present study, multiple methods, including site-directed mutagenesis; CRISPR/Cas9 gene editing...

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Detalles Bibliográficos
Autores principales:	Dong, Jingquan, Zhang, Nan, Zhao, Panpan, Li, Jianhua, Cao, Lili, Wang, Xiaocen, Li, Xin, Yang, Ju, Zhang, Xichen, Gong, Pengtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933011/ https://www.ncbi.nlm.nih.gov/pubmed/33681332 http://dx.doi.org/10.3389/fvets.2021.634612

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