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Genetic Association With Pseudomonas aeruginosa Acquisition in Cystic Fibrosis: Influence of Surfactant Protein D and Mannose-Binding Lectin

Background: Pseudomonas aeruginosa (PA) infection in cystic fibrosis (CF) is associated with poor prognosis. Surfactant protein-D (SFTPD) and mannose-binding lectin (MBL) play a critical role in innate immunity and response to bacterial infections. We investigated serum levels and genetic variants o...

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Detalles Bibliográficos
Autores principales: Nourkami-Tutdibi, Nasenien, Freitag, Klemens, Zemlin, Michael, Tutdibi, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933032/
https://www.ncbi.nlm.nih.gov/pubmed/33679736
http://dx.doi.org/10.3389/fimmu.2021.587313