Structure and inhibition mechanism of the human citrate transporter NaCT

Citrate is most well-known as an intermediate in the TCA cycle of the cell. In addition to this essential role in energy metabolism, the tricarboxylate anion also acts as both a precursor and a regulator of fatty acid synthesis (1–3). Thus, the rate of fatty acid synthesis correlates directly with t...

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Detalles Bibliográficos
Autores principales: Sauer, David B., Song, Jinmei, Wang, Bing, Hilton, Jacob K., Karpowich, Nathan K., Mindell, Joseph A., Rice, William J., Wang, Da-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933130/
https://www.ncbi.nlm.nih.gov/pubmed/33597751
http://dx.doi.org/10.1038/s41586-021-03230-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933130/
https://www.ncbi.nlm.nih.gov/pubmed/33597751
http://dx.doi.org/10.1038/s41586-021-03230-x

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