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Structure and inhibition mechanism of the human citrate transporter NaCT
Citrate is most well-known as an intermediate in the TCA cycle of the cell. In addition to this essential role in energy metabolism, the tricarboxylate anion also acts as both a precursor and a regulator of fatty acid synthesis (1–3). Thus, the rate of fatty acid synthesis correlates directly with t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933130/ https://www.ncbi.nlm.nih.gov/pubmed/33597751 http://dx.doi.org/10.1038/s41586-021-03230-x |