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Shared associations identify causal relationships between gene expression and immune cell phenotypes

Genetic mapping studies have identified thousands of associations between common variants and hundreds of human traits. Translating these associations into mechanisms is complicated by two factors: they fall into gene regulatory regions; and they are rarely mapped to one causal variant. One way arou...

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Detalles Bibliográficos
Autores principales: Gasperi, Christiane, Chun, Sung, Sunyaev, Shamil R., Cotsapas, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933159/
https://www.ncbi.nlm.nih.gov/pubmed/33664438
http://dx.doi.org/10.1038/s42003-021-01823-w