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Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN

The liver plays an important role in lipid and glucose metabolism. Here, we show the role of human antigen R (HuR), an RNA regulator protein, in hepatocyte steatosis and glucose metabolism. We investigated the level of HuR in the liver of mice fed a normal chow diet (NCD) and a high-fat diet (HFD)....

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Detalles Bibliográficos
Autores principales: Tian, Mi, Wang, Jingjing, Liu, Shangming, Li, Xinyun, Li, Jingyuan, Yang, Jianmin, Zhang, Cheng, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933173/
https://www.ncbi.nlm.nih.gov/pubmed/33664225
http://dx.doi.org/10.1038/s41419-021-03514-0