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Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury

The vesicular nucleotide transporter (VNUT) is responsible for the vesicular storage and release of ATP from various ATP-secreting cells, and it plays an essential role in purinergic signaling. Although extracellular ATP and its degradation products are known to mediate various inflammatory response...

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Detalles Bibliográficos
Autores principales: Hasuzawa, Nao, Tatsushima, Keita, Wang, Lixiang, Kabashima, Masaharu, Tokubuchi, Rie, Nagayama, Ayako, Ashida, Kenji, Ogawa, Yoshihiro, Moriyama, Yoshinori, Nomura, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933178/
https://www.ncbi.nlm.nih.gov/pubmed/33664289
http://dx.doi.org/10.1038/s41598-021-83144-w