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Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury
The vesicular nucleotide transporter (VNUT) is responsible for the vesicular storage and release of ATP from various ATP-secreting cells, and it plays an essential role in purinergic signaling. Although extracellular ATP and its degradation products are known to mediate various inflammatory response...
Autores principales: | Hasuzawa, Nao, Tatsushima, Keita, Wang, Lixiang, Kabashima, Masaharu, Tokubuchi, Rie, Nagayama, Ayako, Ashida, Kenji, Ogawa, Yoshihiro, Moriyama, Yoshinori, Nomura, Masatoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933178/ https://www.ncbi.nlm.nih.gov/pubmed/33664289 http://dx.doi.org/10.1038/s41598-021-83144-w |
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