N-Glycosylation can selectively block or foster different receptor–ligand binding modes

While DNA encodes protein structure, glycans provide a complementary layer of information to protein function. As a prime example of the significance of glycans, the ability of the cell surface receptor CD44 to bind its ligand, hyaluronan, is modulated by N-glycosylation. However, the details of thi...

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Detalles Bibliográficos
Autores principales: Vuorio, Joni, Škerlová, Jana, Fábry, Milan, Veverka, Václav, Vattulainen, Ilpo, Řezáčová, Pavlína, Martinez-Seara, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933184/
https://www.ncbi.nlm.nih.gov/pubmed/33664400
http://dx.doi.org/10.1038/s41598-021-84569-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933184/
https://www.ncbi.nlm.nih.gov/pubmed/33664400
http://dx.doi.org/10.1038/s41598-021-84569-z

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