Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice

In humans and mice, inactivating mutations in fibroblast growth factor receptor 1 (Fgfr1) lead to gonadotropin-releasing hormone (GnRH) deficiency and a host of downstream reproductive disorders. It was unclear if Fgfr1 signaling directly upon GnRH neurons critically drove the establishment of a fun...

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Detalles Bibliográficos
Autores principales: Dela Cruz, Cynthia, Horton, Cassandra A., Sanders, Kelsey N., Andersen, Nathan D., Tsai, Pei-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933197/
https://www.ncbi.nlm.nih.gov/pubmed/33679600
http://dx.doi.org/10.3389/fendo.2020.588459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933197/
https://www.ncbi.nlm.nih.gov/pubmed/33679600
http://dx.doi.org/10.3389/fendo.2020.588459

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