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Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential

Cucurbitacin B (CuB) is a widely available triterpenoid molecule that exhibits various biological activities. Previous studies on the anti-tumour mechanism of CuB have mostly focused on cell apoptosis, and research on the ferroptosis-inducing effect has rarely been reported. Herein, we first discove...

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Detalles Bibliográficos
Autores principales: Huang, Shuai, Cao, Bihui, Zhang, Jinling, Feng, Yunfei, Wang, Lu, Chen, Xiaopei, Su, Hang, Liao, Shengrong, Liu, Jinggong, Yan, Jun, Liang, Baoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933245/
https://www.ncbi.nlm.nih.gov/pubmed/33664249
http://dx.doi.org/10.1038/s41419-021-03516-y