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Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC

Cutaneous squamous cell carcinoma (cSCC) is prevalent in the world, accounting for a huge part of non-melanoma skin cancer. Most cSCCs are associated with a distinct pre-cancerous lesion, the actinic keratosis (AK). However, the progression trajectory from normal skin to AK and cSCC has not been ful...

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Detalles Bibliográficos
Autores principales: Zhang, Guolong, Yan, Guorong, Fu, Zhiliang, wu, Yuhao, Wu, Fei, Zheng, Zhe, Fang, Shan, Gao, Ying, Bao, Xunxia, Liu, Yeqiang, Wang, Xiuli, Zhu, Sibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933246/
https://www.ncbi.nlm.nih.gov/pubmed/33664254
http://dx.doi.org/10.1038/s41419-021-03525-x